Study of Acid Phosphatase and Heamoglobin Level in Malarial and Non Malarial Fever Patients

Authors

  • Maneesh Sulya Department of Pathology, Gandhi Medical College, Bhopal M.P.(India)
  • Ummed Singh Solanki Department of Pathology, Gandhi Medical College, Bhopal M.P.(India)

Keywords:

Acid phosphatase, Malaria, Hemoglobin

Abstract

Background: Malaria is a mosquito borne disease. It   is  a  major  health  hazard  in  India  and other  tropical  countries. An estimated 198 million cases of malaria and 584 000 malaria deaths occurred in 2013. Acid  phosphatase  (ec  3.1.3.2,  ACP)  includes  all  the  phosphatases  with  optimal  activity below  the  pH  of  7.0.  ACP  is  present  in  lysosomes  in all  cells  and  exist  extra-lysosomally  in  erythrocytes. Little is known about the levels of ACP in infectious diseases like malaria. So we undertook this study to know the Hb and ACP level in malarial patients.

Methods: 60 subjects in the age group of 20 to 50 years were included in this study. These subjects were divided into 2 groups. Group 1 included 30 confirmed malaria fever patients. Group 2 included 30 non-malarial fever patients of same age & sex group.  These selected subjects had no prostate problems, previous anaemia, or any other kind of bone disorder. Serum ACP was estimated using kit method

Result: The  serum  ACP  levels  were  significantly  increased  in  malarial fever patients when   compared  with  the  non  malaria fever patients (P=0.032). There is also statistical significant difference in the Hb levels between malarial and non-malarial fever patients

Conclusion: Our results of increased levels of serum ACP and decreased Hb in malarial fever patients could be used as a marker for haemolysis & anemia. ACP may be used as an additional investigation in the diagnosis of malaria.

DOI:10.21276/APALM.1515

Author Biography

Maneesh Sulya, Department of Pathology, Gandhi Medical College, Bhopal M.P.(India)

Assistant professor, Department of pathology,Gandhi medical college bhopal m.p.

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Published

27-02-2018

How to Cite

1.
Sulya M, Solanki US. Study of Acid Phosphatase and Heamoglobin Level in Malarial and Non Malarial Fever Patients. Ann of Pathol and Lab Med [Internet]. 2018 Feb. 27 [cited 2025 Feb. 5];5(2):A118-121. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1515

Issue

Vol. 5 No. 2 (2018)

Section

Original Article

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Copyright (c) 2018 Maneesh Sulya, Ummed Singh Solanki

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