Primary schwannoma of thyroid gland in an adolescent male: a rare case-report with review of literature

Authors

  • Pallavi Agrawal M.D., DNB, PDCC (Neuropathology) Consultant Pathologist Department of Pathology, Mahavir Cancer Institute & Research Centre, Patna – 801505 (Bihar), India
  • Neha Garg DNB Resident, Department of Pathology, Mahavir Cancer Institute & Research Centre, Patna – 801505 (Bihar), India
  • Preeti Jain Head of Department of Surgery, Mahavir Cancer Institute & Research Centre, Patna – 801505 (Bihar), India

Keywords:

Isthmus, Schwannoma, Thyroid gland

Abstract

Primary neural tumors of thyroid are very rare and are mainly represented by schwannomas and malignant peripheral nerve sheath tumors. This report presents a rare case of schwannoma involving the isthmus of thyroid in an 11-year adolescent male. The patient presented with soft neck mass which moved with deglutition. The histological examination indicated Antoni A type schwannoma. The clinical, radiological and pathological findings of the tumor are discussed emphasizing the difficulty in reaching a correct diagnosis and planning out exact surgical treatment of the patient. Only 20 cases of primary schwannoma of thyroid gland have so far been described in literature and this is the first case report describing this entity in an adolescent age group.

References

1. Rohaizak M, Meah FA. Cervical Sympathetic Schwannoma Simulating a Thyroid Nodule. Med J Malaysia 2002; 57:218 - 20.
2. Cashman E, Skinner L J, Timon C. Thyroid Swelling: An Unusual Presentation of a Cervical Sympathetic Chain Schwannoma. Medscape 2008; 10(8): 201.
3. Graceffa G, Cipolla C Florena AM, Gentile I, Pompei G,Latteri MA. Primary schwannoma of the thyroid gland involving the isthmus: report of a case. Surgery Today. 2012; 1.
4. Delaney WE, Fry KE. Neurilemmoma of the thyroid gland. Ann Surg. 1964; 160: 1014 - 6.
5. Frantz VK. Pathology of thyroid. In: Warner SC, editor. The thyroid: a fundamental and clinical text. 2nded. New York: Harper and Row. 1962; 321.
6. Million RR, Cassisi NJ. Management of head and neck cancer. Philadelphia: Lippincott. 2nd ed, 1994; 785-810.
7. Goldstein J, Tovi F, Siddi J. Primary Schwannoma of thyroid gland. IntSurg J. 1982; 67: 433-4.
8. Aoki T, Kumeda S, Iwasa T, Inokawa K, Hori T, Makiuchi M. Primary neurilemoma of the thyroid gland: report of a case. Surg Today. 1993; 23: 265 – 268.
9. Mikosch P, Gallowitsch HJ, Kresnik E, Lind P. Schwannoma of the neck simulating a thyroid nodule, Thyroid. 1997; 7(3): 449 - 51.
10. R Sugita, T Nomura, F Yuda, Primary Schwannoma of the Thyroid Gland: CT Findings , AJR. 1998: 171.
11. Jayaram G; Schwannoma of thyroid diagnosed by fine needle aspiration cytology. Acta Cytologica. 1999; 43: 743 - 744.
12. Al-Ghamdi S, Fageeh N, Dewan M. Malignant schwannoma of the thyroid gland. Otolaryngol Head Neck Surg. 2000; 122: 143–144.
13. Gustafson LM, Liu JH, Rutter MJ, Stern Y, Cotton RT ; Primary neurilemoma of the thyroid gland: a case report; Am J Otolaryngol. 2001 Jan-Feb; 22(1): 84 - 86.
14. Yoshiyuki I, Takemi T, Katsuyoshi H. A case of schwannoma of the thyroid. J JpnSurgAssoc. 2003; 64: 2105 – 2108.
15. Baglaj M, Markowska-Woyciechowska A, Sawicz-Birkowska K, Dorobisz U. Primary neurilemmoma of the thyroid gland in a 12-year-old girl. J PediatrSurg. 2004; 39: 1418 – 1420.
16. De Paoli F, Giugliano G, Casadio C, Tredici P, Bruschini R, De Fiori E.Schwannoma of thyroid bed. A case report and considerations on interdisciplinary collaboration. Acta Otorhinolaryngol Ital 2005; 25: 250-254.
17. Aron, M., Kapila, K. and Verma, K. Neural tumours of the neck presenting as thyroid nodules: a report of three cases. Cytopathology. 2005; 16: 206 –209.
18. Magro G, Torrisi A, Amico P, Lo Presti C, Ippolito G, Ippolito O. Ancient schwannoma of the thyroid. Am J Case Rep. 2008; 9: 182 – 187.
19. Uri O, Baron E, Lefel O, BittermanA. Primary schwannoma of the thyroid gland presenting as an asymptomatic cold nodule. American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 2009; 30(6): 427 – 429.
20. Subramaniam V, Adarsha TV, Khandige S. SchwannomaOf The Thyroid Gland – A Case Report. Jurnalul de Chirurgie Iasi. 2010; 6(4).
21. Mangal N, Agarwal A K, Sharma VK, Sharma S; Neurilemmoma of the thyroid gland : A rare case presentation ,Indian Journal of Pathology and Microbiology. 2010; 53(4).
22. J Ann, Y L Oh , J S Shin , H S Sheong: Primary Schwannoma of thyroid gland ,Acta Cytologica. 2010; 54.
23. Ibrahim WG, Khalek MSA, Crawford BE, Kandil EH. Hoarseness due to thyroid mass. The Journal of Medicine. 2011; 69(1): 39 - 40.
24. Dhar DH, Dabholkar DJP, Kandalkar DB, Godke DR. Primary thyroid Schwannoma Masquerading as a thyroid nodule: A case report with review of literature. SEAJCRR. 2014; 3(3): 755 - 763.

Downloads

Additional Files

Published

21-02-2016

How to Cite

1.
Agrawal P, Garg N, Jain P. Primary schwannoma of thyroid gland in an adolescent male: a rare case-report with review of literature. Ann of Pathol and Lab Med [Internet]. 2016 Feb. 21 [cited 2024 Dec. 21];3(1):C1-5. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm442

Issue

Vol. 3 No. 1 (2016)

Section

Case Report

License

Copyright (c) 2016 Pallavi Agrawal, Neha Garg, Preeti Jain

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).