Unusual sites of metastasis of breast carcinoma to gallbladder and colon
Keywords:
breast carcinoma, unusual metastasis, gall blabber, intestineAbstract
Breast cancer is usually associated with metastasis to lungs, bones and liver. Metastatic pattern of Infiltrating Lobular Carcinoma differs from Infiltrating Ductal Carcinoma with higher frequency of tumor extension to bone, gastrointestinal tract, genital tract, meninges and serosa. We here present two rare case reports showing this unusual pattern of metastasis of infiltrating lobular breast carcinoma to colon and gall bladder. Because of its rarity, nonspecific clinical presentation and the variable radiographic features, the diagnosis of intestinal and biliary tract metastasis by breast carcinoma is difficult.
References
2. Eljabu W, Finch G, Nottingham J, Vaingankar N. Metastatic deposits of breast lobular carcinoma to small bowel and rectum. Int J Breast Cancer. 2011; 413949.
3. Di Vita M, Zanghì A, Lanzafame S, Cavallaro A, Piccolo G, Berretta M, Grosso G, Cappellani A. Gallbladder metastases of breast cancer: from clinical-pathological patterns to diagnostic and therapeutic strategy. Clin Ter. 2011; 162:451-6.
4. Yoon WJ, Yoon Y B, Kim Y J, Ryu J K, KimY T. Metastasis to the gallbladder: A single-center experience of 20 cases in South Korea. World J Gastroenterol. 2009; 14; 15: 4806-9.
5. Shah RJ, Koehler A, and Long J D. Bile peritonitis secondary to breast cancer metastatic to the gallbladder. American Journal of Gastroenterology. 2000; 95,1379–81.
6. Borst M J, Ingold J A. Metastatic patterns of invasive lobular versus invasive ductal carcinoma of the breast. Surgery. 1993;114(4):637-41
7. Washington K and McDonagh D. Secondary tumors of the gastrointestinal tract: surgical pathologic findings and comparison with autopsy survey. Modern Pathology. 1995; 8, 427–433.
8. Yokota T, Kunii Y, Kagami M, Yamada Y, Takahashi M, Kikuchi S, Nakamura M, Yamauchi H. Metastatic breast carcinoma masquerading as primary colon cancer. Am J Gastroenterol. 2000;95:3014–6.
9. Zagouri F, Sergentanis TN, Koulocheri D, Nonni A, Bousiotou A, Domeyer P, Michalopoulos N V, Dardamanis D, Konstadoulakis M M and Zografos G C. Bilateral synchronous breast carcinomas followed by a metastasis to the gall bladder: a case report. World J Surg Oncol. 2007; 5: 101.
10. Murguia E Quiroga D Canteros G,Cesar SanMartino.Gallbladder metastases from ductal papillary carcinoma of the breast. Journal of Hepato-Biliary-Pancreatic Surgery November 2006, 13:591-593.
11. Ferlicot S, Vincent-Salomon A, Médioni J, Genin P, Rosty C, Sigal-Zafrani B, Fréneaux P, Jouve M, Thiery JP, SastreGarau X. Wide metastatic spreading in infiltrating lobular carcinoma of the breast. European Journal of Cancer. 2004; 40:336–41.
12. Ikeda Y, Morita N, Ikeda T. Metachronous rectal metastasis from invasive ductal carcinoma of male breast. Endoscopy. 2008;40:108-9.
13. Smith NZ. Treating metastatic breast cancer with systemic chemotherapies: current trends and future perspectives. Clin J Oncol Nurs. 2012;16:33–43
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2016 Sabah Nayef Nemri, Nazima Haider, Sohaila Fatima, Bouvier Francis Valere D’sa
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).