Unusual sites of metastasis of breast carcinoma to gallbladder and colon
Keywords:
breast carcinoma, unusual metastasis, gall blabber, intestineAbstract
Breast cancer is usually associated with metastasis to lungs, bones and liver. Metastatic pattern of Infiltrating Lobular Carcinoma differs from Infiltrating Ductal Carcinoma with higher frequency of tumor extension to bone, gastrointestinal tract, genital tract, meninges and serosa. We here present two rare case reports showing this unusual pattern of metastasis of infiltrating lobular breast carcinoma to colon and gall bladder. Because of its rarity, nonspecific clinical presentation and the variable radiographic features, the diagnosis of intestinal and biliary tract metastasis by breast carcinoma is difficult.
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2. Eljabu W, Finch G, Nottingham J, Vaingankar N. Metastatic deposits of breast lobular carcinoma to small bowel and rectum. Int J Breast Cancer. 2011; 413949.
3. Di Vita M, Zanghì A, Lanzafame S, Cavallaro A, Piccolo G, Berretta M, Grosso G, Cappellani A. Gallbladder metastases of breast cancer: from clinical-pathological patterns to diagnostic and therapeutic strategy. Clin Ter. 2011; 162:451-6.
4. Yoon WJ, Yoon Y B, Kim Y J, Ryu J K, KimY T. Metastasis to the gallbladder: A single-center experience of 20 cases in South Korea. World J Gastroenterol. 2009; 14; 15: 4806-9.
5. Shah RJ, Koehler A, and Long J D. Bile peritonitis secondary to breast cancer metastatic to the gallbladder. American Journal of Gastroenterology. 2000; 95,1379–81.
6. Borst M J, Ingold J A. Metastatic patterns of invasive lobular versus invasive ductal carcinoma of the breast. Surgery. 1993;114(4):637-41
7. Washington K and McDonagh D. Secondary tumors of the gastrointestinal tract: surgical pathologic findings and comparison with autopsy survey. Modern Pathology. 1995; 8, 427–433.
8. Yokota T, Kunii Y, Kagami M, Yamada Y, Takahashi M, Kikuchi S, Nakamura M, Yamauchi H. Metastatic breast carcinoma masquerading as primary colon cancer. Am J Gastroenterol. 2000;95:3014–6.
9. Zagouri F, Sergentanis TN, Koulocheri D, Nonni A, Bousiotou A, Domeyer P, Michalopoulos N V, Dardamanis D, Konstadoulakis M M and Zografos G C. Bilateral synchronous breast carcinomas followed by a metastasis to the gall bladder: a case report. World J Surg Oncol. 2007; 5: 101.
10. Murguia E Quiroga D Canteros G,Cesar SanMartino.Gallbladder metastases from ductal papillary carcinoma of the breast. Journal of Hepato-Biliary-Pancreatic Surgery November 2006, 13:591-593.
11. Ferlicot S, Vincent-Salomon A, Médioni J, Genin P, Rosty C, Sigal-Zafrani B, Fréneaux P, Jouve M, Thiery JP, SastreGarau X. Wide metastatic spreading in infiltrating lobular carcinoma of the breast. European Journal of Cancer. 2004; 40:336–41.
12. Ikeda Y, Morita N, Ikeda T. Metachronous rectal metastasis from invasive ductal carcinoma of male breast. Endoscopy. 2008;40:108-9.
13. Smith NZ. Treating metastatic breast cancer with systemic chemotherapies: current trends and future perspectives. Clin J Oncol Nurs. 2012;16:33–43
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Published
21-02-2016
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Nemri SN, Haider N, Fatima S, Valere D’sa BF. Unusual sites of metastasis of breast carcinoma to gallbladder and colon. Ann of Pathol and Lab Med [Internet]. 2016 Feb. 21 [cited 2024 Dec. 5];3(1):C6-9. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm495
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Copyright (c) 2016 Sabah Nayef Nemri, Nazima Haider, Sohaila Fatima, Bouvier Francis Valere D’sa
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