Mermaids are real !! Sirenomelia: A case of mermaid baby
Keywords:
Sirenomelia, Mermaid, Polymalformative SyndromeAbstract
We report a case of sirenomelia baby (mermaid syndrome) born to a thirty years old female at 36 weeks of gestation. It is a rare syndrome in which there is fusion of lower limbs.
Classification of caudal regression syndrome (CRS) from sirenomelia is still debated. According to some authors, this syndrome should be classified separately from caudal regression syndrome and is likely to be the result of an abnormality taking place during the fourth gestational week, causing developmental abnormalities in the lower extremities, pelvis, genitalia, urinary tract and digestive organs. Despite recent progress in pathology, the etiopathogenesis of sirenomelia is still debated.Â
References
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2. Banerjee A, Faridi MM, Banerjee TK, Mandal RN, Aggarwal A. Sirenomelia. Indian J Pediatr. 2003;70(7):589–91
3. Mohammed Z. Seidahmed, Omer B. Abdelbasit, Khalid A. Alhussein,Abeer M. Miqdad, Mohammed I. Khalil, Mustafa A. Salih, Sirenomelia and severe caudal regression syndrome.Saudi Med J 2014;35:S36-S43
4. Mills JL, Baker L, Goldman AS. Malformations in infants of diabetic mothers occur before the seventh gestational week. Implications for treatment. Diabetes.1979;28:292–293.
5. Anis Fadhlaoui, Mohamed Khrouf, Soumaya Gaigi, Fethi Zhioua, Anis Chaker. The Sirenomelia Sequence: A Case History. Clin Med Insights Case Rep. 2010; 3: 41–49.
6. Stocker JT, Heifetz SA. Sirenomelia. A morphological study of 33 cases and review of the literature. Perspect Pediatr Pathol 1987; 10: 7-50.
7. Stevenson RE. Limbs. In: Stevenson RE, Hall JG, editors. Human malformations and related anomalies. 2nd ed. New York (NY): Oxford University Press; 2006. p. 835-925.
8. Orioli IM, Amar E, Arteaga-Vazquez J, Bakker MK, Bianca S, Botto LD, et al. Sirenomelia: an epidemiologic study in a large dataset from the International Clearinghouse of Birth Defects Surveillance and Research, and literature review. Am J Med Genet C Semin Med Genet 2011; 157C: 358-373.
9. Duhamel B. From the mermaid to anal imperforation: the syndrome of caudal regression. Arch Dis Child 1961; 36: 152-5.
10. Jones KL. Philadelphia (PA): Elsevier Saunders; 2006. Smith's Recognizable Patterns of Human Malformation; pp. 728–729.
11. Stevenson RE, Jones KL, Phelan MC, et al. Vascular steal: the pathogenic mechanism producing sirenomelia and associated defects of viscera and soft tissues. Pediatrics.1986;78:451–7.
12. Adra A, Cordero D, Mejides A, et al. Caudal regression syndrome: Etio-pathogenesis, prenatal diagnosis and perinatal management. Obstet Gynecol Surv. 1994;49(7):508–76.
13. Dilorenzo M, Brandt ML, Veilleux A. Sirenomelia in an identical twin. A case report. J Pediatr Surg. 1991;26:1334.
14. Murphy JJ, Fraser GC, Blair GK. Sirenomelia: case of a surviving mermaid. J Ped Surg. 1992:27;(10):1265–8.
15. S.K. Samal, S. Rathod .Sirenomelia: The mermaid syndrome: Report of two cases. J Nat Sci Biol and Med. 2015; 6: 264–266
2. Banerjee A, Faridi MM, Banerjee TK, Mandal RN, Aggarwal A. Sirenomelia. Indian J Pediatr. 2003;70(7):589–91
3. Mohammed Z. Seidahmed, Omer B. Abdelbasit, Khalid A. Alhussein,Abeer M. Miqdad, Mohammed I. Khalil, Mustafa A. Salih, Sirenomelia and severe caudal regression syndrome.Saudi Med J 2014;35:S36-S43
4. Mills JL, Baker L, Goldman AS. Malformations in infants of diabetic mothers occur before the seventh gestational week. Implications for treatment. Diabetes.1979;28:292–293.
5. Anis Fadhlaoui, Mohamed Khrouf, Soumaya Gaigi, Fethi Zhioua, Anis Chaker. The Sirenomelia Sequence: A Case History. Clin Med Insights Case Rep. 2010; 3: 41–49.
6. Stocker JT, Heifetz SA. Sirenomelia. A morphological study of 33 cases and review of the literature. Perspect Pediatr Pathol 1987; 10: 7-50.
7. Stevenson RE. Limbs. In: Stevenson RE, Hall JG, editors. Human malformations and related anomalies. 2nd ed. New York (NY): Oxford University Press; 2006. p. 835-925.
8. Orioli IM, Amar E, Arteaga-Vazquez J, Bakker MK, Bianca S, Botto LD, et al. Sirenomelia: an epidemiologic study in a large dataset from the International Clearinghouse of Birth Defects Surveillance and Research, and literature review. Am J Med Genet C Semin Med Genet 2011; 157C: 358-373.
9. Duhamel B. From the mermaid to anal imperforation: the syndrome of caudal regression. Arch Dis Child 1961; 36: 152-5.
10. Jones KL. Philadelphia (PA): Elsevier Saunders; 2006. Smith's Recognizable Patterns of Human Malformation; pp. 728–729.
11. Stevenson RE, Jones KL, Phelan MC, et al. Vascular steal: the pathogenic mechanism producing sirenomelia and associated defects of viscera and soft tissues. Pediatrics.1986;78:451–7.
12. Adra A, Cordero D, Mejides A, et al. Caudal regression syndrome: Etio-pathogenesis, prenatal diagnosis and perinatal management. Obstet Gynecol Surv. 1994;49(7):508–76.
13. Dilorenzo M, Brandt ML, Veilleux A. Sirenomelia in an identical twin. A case report. J Pediatr Surg. 1991;26:1334.
14. Murphy JJ, Fraser GC, Blair GK. Sirenomelia: case of a surviving mermaid. J Ped Surg. 1992:27;(10):1265–8.
15. S.K. Samal, S. Rathod .Sirenomelia: The mermaid syndrome: Report of two cases. J Nat Sci Biol and Med. 2015; 6: 264–266
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25-02-2016
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Gupta AP, Parate SN, Kumbhalkar D. Mermaids are real !! Sirenomelia: A case of mermaid baby. Ann of Pathol and Lab Med [Internet]. 2016 Feb. 25 [cited 2024 Dec. 26];3(1):C49-52. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm500
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Copyright (c) 2016 Anupama Praveen Gupta, Sanjay Nanaji Parate, Dinkar Kumbhalkar
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