Spectrum of Cervical Cytological Lesions in Premenopausal and Postmenopausal Women

Authors

  • Vaishali Baburao Nagose Department of Pathology, Mamata Medical College, Rotary Nagar, Khammam-507002. Telangana
  • Nirvana Rasaily Halder Department of Pathology, Mamata Medical College, Rotary Nagar, Khammam-507002. Telangana
  • Shruthi Amit Deshpande Department of Pathology, Mamata Medical College, Rotary Nagar, Khammam-507002. Telangana
  • Shivanand Shriram Rathod Department of Pathology, Mamata Medical College, Rotary Nagar, Khammam-507002. Telangana
  • Varsha Ashok Jadhav Department of Pathology, Mamata Medical College, Rotary Nagar, Khammam-507002. Telangana

Keywords:

Pap smear, Premenopausal, Postmenopausal, ASCUS, HSIL, SCC

Abstract

Background:Screening with Pap smear initially targets women with higher prevalence of high grade precancerous cervical lesions [Cervical Intraepithelial Neoplasia 2/3 (CIN2/CIN3)] - women mostly in their third and fourth decade. But different conditions affect uterine cervix, including non neoplastic & neoplastic diseases, at different age. Thus, the Pap smears findings should vary in premenopausal & post menopausal groups.

Methods: A prospective study of two years was conducted to screen Pap smears in women who were categorised as premenopausal age group <46 years & postmenopausal ≥46years.

Result: A total of 6647 cases were analysed within age ranging from 18 to 85 years. 5369 (80.77%) patients were in premenopausal & 1278 (19.23%) in postmenopausal age group. Premenopausal group showed interpretation as “Negative for Intraepithelial Lesion or Malignancy†(NILM) in 97.56%. Here, two of the three cases of Squamous Cell Carcinoma (SCC) were of < 40 years. Postmenopausal age group showed maximum cases of Atypical Squamous Cells of Undetermined Significance (ASCUS), Low Grade Squamous Intraepithelial Lesion (LSIL) & SCC. Maximum cases of High-Grade Squamous Intraepithelial Lesion (HSIL) belonged to >60 years.

Conclusion: It is suggested that the Pap screening should not be ceased, but be continued beyond 60 years of age. In premenopausal age, along with SIL, the possibility of malignancy should not be neglected & infections should also be paid more attention. Thus, irrespective of the age of female after 30 yrs, it is highly recommended for them to undergo PAP screening. 

DOI: 10.21276/APALM.1661

Author Biography

Vaishali Baburao Nagose, Department of Pathology, Mamata Medical College, Rotary Nagar, Khammam-507002. Telangana

Assistant Professor, Department of Pathology, Mamata Medical College, Khammam, Telangana, India.

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Published

22-12-2017

How to Cite

1.
Nagose VB, Halder NR, Deshpande SA, Rathod SS, Jadhav VA. Spectrum of Cervical Cytological Lesions in Premenopausal and Postmenopausal Women. Ann of Pathol and Lab Med [Internet]. 2017 Dec. 22 [cited 2025 Feb. 5];4(6):A795-800. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1661

Issue

Vol. 4 No. 6 (2017)

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Original Article

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Copyright (c) 2017 Vaishali Baburao Nagose, Nirvana Rasaily Halder, Shruthi Amit Deshpande, Shivanand Shriram Rathod, Varsha Ashok Jadhav

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