Basaloid Squamous Cell Carcinoma of Palpebral Conjunctiva: A Rare Case Report

Authors

  • Ankita Shende Department of Pathology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion
  • Neha Sharma Department of Pathology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion
  • Madhu Chaturvedi Department of Pathology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion
  • Renuka Kulkarni Department of Pathology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion
  • Yogeshwari Mane Department of Pathology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion

DOI:

https://doi.org/10.21276/apalm.3282

Keywords:

Basaloid squamous cell carcinoma, conjunctiva, basal cell carcinoma, adenoid cystic carcinoma, squamous cell carcinoma

Abstract

Basaloid squamous cell carcinoma (BSCC) is a rare variant of squamous cell carcinoma that commonly affects the upper aerodigestive tract. It is usually seen in elderly male patients. Clinically, BSCC is an aggressive tumour with high rates of nodal and distant metastasis. Palpebral conjunctiva is an unusual site for occurrence of BSCC and only three cases are published in literature till date to the best of our knowledge. BSCC can mimic various other tumours on histopathology and can pose as a diagnostic dilemma on histopathology reporting. Therefore, diagnosis of BSCC, though at a rarer site such as the palpebral conjunctiva is imperative. We report a case of BSCC of left palpebral conjunctiva in a 61-year-old female which was treated successfully after recurrence.

References

Wain SL, Kier R, Vollmer RT, Bossen EH. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Human Pathol. 1986 Nov;17(11):1158-66.

Shanmugaratnam K, Sobin LH. The World Health Organization histological classification of tumours of the upper respiratory tract and ear. A commentary on the second edition. Cancer. 1993 Apr 15;71(8):2689-97.

McHugh BJ. Rosai And Ackermann’s Surgical Pathology. 11th ed. China; 2018. Chapter 4, Upper Aerodigestive tract; p. 156.

Myers LJ. Rosai And Ackermann’s Surgical Pathology. 11th ed. China; 2018. Chapter 10, Lung; p. 406.

Vasudev P, Boutross-Tadross O, Radhi J. Basaloid squamous cell carcinoma: two case reports. Cases J. 2009 Dec;2:1-4.

Mathur SK, Jain P, Batra A, Sen R. Basaloid squamous cell carcinoma of conjunctiva: A rare entity. Indian J Cancer. 2014 Oct 1;51(4):469.

Liu YC, Chen N, Hsu YH, Sheu MM, Tsai RK. Basaloid squamous cell carcinoma of the conjunctiva. Ophthalmic Plast Reconstr Surg. 2015 Mar 1;31(2):e28-30.

Oikawa K, Tabuchi K, Nomura M, Okubo H, Wada T, Iijima T, Hara A. Basaloid squamous cell carcinoma of the maxillary sinus: a report of two cases. Auris Nasus Larynx. 2007 Mar 1;34(1):119-23.

Soriano E, Faure C, Lantuejoul S, Reyt E, Bolla M, Brambilla E, Righini CA. Course and prognosis of basaloid squamous cell carcinoma of the head and neck: a case–control study of 62 patients. Eur J Cancer. 2008 Jan 1;44(2):244-50.

Myers LJ. Rosai And Ackermann’s Surgical Pathology. 11th ed. China; 2018. Chapter 10, Lung; p. 407-409.

Husain SE, Patrinely JR, Zimmerman LE, Font RL. Primary basal cell carcinoma of the limbal conjunctiva. Ophthalmology. 1993 Nov 1;100(11):1720-2.

Kirkham N. Lever’s Histopathology Of The Skin. 10th ed. India; 2013. Chapter 29, Tumors and Cysts of the Epidermis; p. 823-835.

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Published

04-02-2024

How to Cite

1.
Shende A, Sharma N, Chaturvedi M, Kulkarni R, Mane Y. Basaloid Squamous Cell Carcinoma of Palpebral Conjunctiva: A Rare Case Report. Ann of Pathol and Lab Med [Internet]. 2024 Feb. 4 [cited 2024 Nov. 3];11(2):C23-28. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/3282

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Section

Case Report