Castleman's Disease of the Chest Wall Masquerading as a Breast Mass

Authors

  • Meenu Gill Department of Pathology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
  • Kritika Lohumi Department of Pathology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
  • Mahak Dahiya Department of Pathology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
  • Sanjeev Parshad Department of Surgery, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
  • Veena Gupta Department of Pathology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
  • Promil Jain Department of Pathology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
  • Sunita Singh Department of Pathology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.

DOI:

https://doi.org/10.21276/apalm.3603

Keywords:

Castleman Disease, Lymphoproliferative Disorders, Unicentric , Hyaline-Vascular Type

Abstract

Castleman's disease (CD) is a rare lymphoproliferative disorder with unknown etiology and is clinically associated with abnormal lymph node enlargement. CD is classified clinically as unicentric CD (UCD) or multicentric CD (MCD) and histologically as hyaline vascular variant (HVV) or plasma cell variant (PCV). Primary axillary localization of CD represents 2% of the cases. CD rarely occurs in the breasts. The CD is easily confused with lymphoma or other solid tumors. However, the infrequent occurrence of CD has led to a limited analysis of its clinical presentation and susceptibility to misdiagnosis during preliminary investigations. Therefore, accurate diagnosis requires clinical, radiological, and histopathological evaluation. We herein describe a rare case of CD in a 38-year-old female who initially presented with a swelling in the right breast. CECT as well as FNAC of the lesion was suggestive of a mesenchymal tumor. The patient underwent axillary-wide local excision.

References

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Published

30-07-2025

How to Cite

1.
Gill M, Lohumi K, Dahiya M, Parshad S, Gupta V, Jain P, et al. Castleman’s Disease of the Chest Wall Masquerading as a Breast Mass. Ann of Pathol and Lab Med [Internet]. 2025 Jul. 30 [cited 2025 Dec. 5];12(7):C101-105. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/3603

Issue

Vol. 12 No. 7 (2025)

Section

Case Report

License

Copyright (c) 2025 Meenu Gill, Kritika Lohumi, Mahak Dahiya, Sanjeev Parshad, Veena Gupta, Promil Jain, Sunita Singh

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