Malignant Sacrococcygeal Teratoma with Yolk Sac Differentiation: A Rare Case Report
DOI:
https://doi.org/10.21276/apalm.3620Keywords:
Sacrococcygeal teratoma, Yolk sac tumour, NeonateAbstract
Sacrococcygeal teratomas (SCTs) are the most common germ cell tumours in neonates and infants, with malignant transformation often observed in postnatal cases. Yolk sac tumour (YST) is the most frequent malignant germ cell component seen in SCTs. We report a case of a 3-month-old infant presenting with a Type II SCT, showing histopathological features of yolk sac tumour differentiation.
References
1. Nasreen S, Rahman M, Mosarrat S, Sharmin T, Rahman M. Malignant Sacrococcygeal Teratoma with Yolk Sac Differentiation in a Child-A Case Presentation. Open Journal of Pathology. 2018:8:60-67. doi: 10.4236/ojpathology.2018.82007.
2. Philip A, Pizzodevaid G, Poplack D, Harris L, Ed. Germs cell tumors. In: Devita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: Principles & Practice of Oncology. 4th ed. JB Lippincott Co; 1993.
3. Reaman GH, Cohan LF. Less frequently encountered malignant neoplasms. In: Levine AS, ed. Cancer in the Young. New York: Masson Publ; 1982:707-727.
4. Young JL, Miller RW, Incidence of malignant tumors in US children. J Pediatr. 1975:86:254-258.
5. Altman RP, Randolph JG, Lilly JR. Sacrococcygeal teratoma: American Academy of Pediatrics Surgical Section survey-1973. J Pediatr Surg. 1974 9:389-398.
6. Khanchel-Lakhoua F, Koubâa-Mahjoub W, Jouini R, Bel Haj Salah M, Kaabar N, Chadli-Debbiche A. Sacrococcygeal yolk sac tumor: an uncommon site. APSP J Case Rep. 2012;3(3):17.
7. Schneider DT, Wessalowski R, Calaminus G, et al. Treatment of recurrent malignant sacrococcygeal germ cell tumors: analysis of 22 patients registered in the German protocols MAKEI 83/86, 89, and 96. J Clin Oncol. 2001;19(7):1951-60.
8. Zynger DL, Dimov ND, Luan C, Teh BT, Yang XJ. Glypican 3: a novel marker in testicular germ cell tumors. Am J Surg Pathol. 2006;30(12):1570-5.
9. Miettinen M, Wang Z. McCue PA, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014;38(3):410-20.
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Copyright (c) 2025 Sayeda Hoosne Harisha, Manoj Barman, Jabin Musfique, Rajib Ray Baruah, Manjula Choudhury
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