Lipoma Masquerading as Soft Tissue Sarcoma: A Rare Case Report

Authors

  • Richa Bhartiya Department of Pathology, GGMC and Sir JJ Group of hospitals, Mumbai, Maharashtra, India
  • Pallavi Mehra Department of Pathology, Patna Medical College, Patna, Bihar, India
  • Naveen Kumar Bariar Department of Pathology, Patna Medical College, Patna, Bihar, India

DOI:

https://doi.org/10.21276/apalm.3634

Keywords:

Lipoma, Liposarcoma, Subcutaneous, Fine-Needle Aspiration

Abstract

Giant lipomas of the head and neck are rare benign tumors that can mimic soft tissue sarcomas. We report the case of a 38-year-old male who presented with a large 25x18 cm posterior neck mass associated with sinus and intermittent low-grade fever for ten days. Routine laboratory tests were normal. Ultrasonography showed a well-defined hypoechoic subcutaneous lesion without cystic areas or calcifications. FNAC demonstrated mature fat cells in strands of fibrous stroma, compatible with a lipoma. A contrast-enhanced CT scan showed no underlying bone or spinal involvement. The mass was surgically excised, and histopathology confirmed the benign diagnosis. No recurrence occurred on follow-up. This case underscores the importance of integrating cytology, imaging, and histopathology to differentiate giant lipomas from malignant tumors and guide clinical decision-making in such rare presentations.

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Published

29-10-2025

How to Cite

1.
Bhartiya R, Mehra P, Bariar NK. Lipoma Masquerading as Soft Tissue Sarcoma: A Rare Case Report. Ann of Pathol and Lab Med [Internet]. 2025 Oct. 29 [cited 2025 Dec. 5];12(10):C176-C179. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/3634

Issue

Section

Case Report