Histopathological Spectrum of Nasal Mass Lesions: A Three-Year Study of 138 Cases at a Tertiary Care Center of Rajasthan
DOI:
https://doi.org/10.21276/apalm.3779Keywords:
nasal mass lesions, paranasal sinuses, histopathology, squamous cell carcinoma, angiofibromaAbstract
Background: Nasal mass lesions represent a heterogeneous group of pathologies ranging from non-neoplastic inflammatory conditions to benign and malignant neoplasms. This study aimed to evaluate the histopathological spectrum of nasal masses over three years.Methods: A retrospective analysis of one thirty eight consecutive cases clinically diagnosed as nasal masses was conducted. Specimens were processed and evaluated histologically. Cases were categorized into non-neoplastic, benign neoplastic, and malignant groups. Demographic data were recorded and analyzed. Result: Non-neoplastic lesions formed the majority, with inflammatory and allergic polyps being the most common. Benign tumors included inverted papilloma and juvenile nasopharyngeal angiofibroma. Malignant tumors, though fewer, included squamous cell carcinoma, nasopharyngeal carcinoma, and sarcomas. Male predominance was noted, with age distribution varying across categories.
Conclusion: Histopathology remains indispensable in distinguishing nasal masses, guiding treatment, and identifying malignant lesions early. Institution-based data add valuable insights into regional patterns of sinonasal pathology.
References
1. Dasgupta A, Ghosh RN, Mukherjee C. Nasal polyps—histopathologic spectrum. Indian J Otolaryngol Head Neck Surg. 1997;49(1):32–7.
2. Garg D, Mathur K. Clinico-pathological study of space occupying lesions of nasal cavity, paranasal sinuses, and nasopharynx. J Clin Diagnost Res. 2014;8(11):FC04–7.
3. Jain SS, Dagar PM, Dagar MK, Passey JC. Histopathological spectrum of sinonasal lesions. Int J Res Med Sci. 2024;12(10):3731-6.
4. Kulkarni AM, Mudholkar VG, Acharya AS, Ramteke RV. Histopathological study of lesions of nose and paranasal sinuses. Indian J Otolaryngol Head Neck Surg. 2011;64(3):275–9.
5. Satarkar RN, Srikanth ST. Tumours and tumour-like conditions of nasal cavity, paranasal sinuses and nasopharynx: A study of 206 cases. Indian J Cancer. 2016;53(4):478–82.
6. Vartak UC, Sarnaik AG, Vartak S, Pathan F. Spectrum of histopathological lesions of nose and paranasal sinuses: A 5-year study. Journal of Medical Society. 2020;34(3):128–38.
7. Li W, Lu H, Zhang H, Sun X, Hu L, Wang D. Squamous cell carcinoma associated with inverted papilloma: Recurrence and prognostic factors. Oncol Lett. 2020;19(2):1082–8.
8. Miao S, Cheng Y, Li Y, Chen X, Chen F, Zha D, Xue T. Prediction of recurrence-free survival and risk factors of sinonasal inverted papilloma after surgery by machine learning models. Eur J Med Res. 2024;29(1):528.
9. Goswami RR, Deuri C, Daimary M, Datta B. Clinicopathological profile of sinonasal masses: a hospital-based study. Asian Pacific Journal of Cancer Care. 2025;10(3):737–40.
10. Shirazi N, Bist SS, Selvi TN, Harsh M. Spectrum of sinonasal tumors: a 10-year experience at a tertiary care hospital in North India. Oman Medical Journal. 2015;30(6):435–40. doi:10.5001/omj.2015.86.
11. Bundela A, Bundela A, Mitra S. The Histopathological study of Lesions of the Nasal Cavity, Paranasal Sinuses and Nasopharynx in Eastern UP, India. Trop J Pathol Microbiol. 2022;8(5):65-70.
12. Joshi C, Bhardwaj A, Swaymprabha S, Mangrulkar K, Bombeshwar V, Varma R. Histopathological study of nasal masses- a 2-year study in a tertiary care hospital. International Journal of Pharmaceutical and Clinical Research. 2024; 16(10); 105-113
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