Seroprevalence of Hepatitis B Surface Antigen positive Patients Attending a Tertiary Care Hospital in Srikakulam, Andhra Pradesh.

Authors

  • Aruna Bula RAJIV GANDHI INSTITUTE OF MEDICAL SCIENCES(RIMS),SRIKAKULAM,ANDHRA PRADESH
  • Santhosh Ram Gaddam ANDHRA MEDICAL COLLEGE,VISAKHAPATNAM,ANDHRA PRADESH

Keywords:

Hepatitis B, HBsAg, Prevalence, Srikakulam.

Abstract

Background: Hepatitis B virus (HBV) infection continues to be a serious public health problem globally and studying the prevalence of HBV infection in a geographical area aids in establishing magnitude of the problem. A teaching hospital based population study of Hepatitis B surface antigen (HBsAg) is a strong indicator of true HBV infection rate in the community as large number of patients from different backgrounds attend the hospital.

Methods: A one step rapid immunochromatographic method for detection of HBsAg was performed to diagnose HBV infection. 24,028 sera samples were tested over a period of one year 9 months.

Result: Out of the 24,028 samples tested for HBsAg, 733 (3.05%) were found to be positive for HBsAg. Positivity rate was more among males 440 (60.02 %) than females 293 (39.97 %) and the most common age group in males was 41-50 years (23.18 %) followed by 31- 40 years (22%).In females, commonest age group was 21-30 years (38.22%) followed by 31-40 years (14.67 %).

Conclusion: The study helps to know the magnitude of viral transmission in the community & to know the at risk age groups.Seroprevalence of HBsAg in Srikakulam, Andhra Pradesh was found to be 3.05% which is in accordance with the national average of 2-7 % and it falls into intermediate zone of HBsAg prevalence according to WHO.

DOI: 10.21276/APALM.2017.1118

Author Biographies

  • Aruna Bula, RAJIV GANDHI INSTITUTE OF MEDICAL SCIENCES(RIMS),SRIKAKULAM,ANDHRA PRADESH
    ASSISTANT PROFESSOR,DEPARTMENT OF MICROBIOLOGY
  • Santhosh Ram Gaddam, ANDHRA MEDICAL COLLEGE,VISAKHAPATNAM,ANDHRA PRADESH
    SENIOR RESIDENT,DEPARTMENT OF ORTHOPAEDICS

References

1. Quadri SA, Dadapeer HJ, Arifulla KM, Khan N. Prevalence of Hepatitis B Surface Antigen in hospital based population in Bijapur,Karnataka. Al Ameen J Med Sci 2013;6(2):180-182.

2. Sood S. Serological Evaluation of Hepatitis B Virus in out patient Department patients of a private Hospital in North —West India. National J of Community Medicine, 2013:4;485-488.

3. Naqshbandi I, Quadri SYA, Yasmeen N, Bashir N. Seroprevalence and Risk Factors of Hepatitis B virus Infection among General Population of Srinagar Kashmir.Int.J of Contem Med Res 2016;3 (4):1050-1054.

4. Sood S, Malvankar S. Seroprevalence of Hepatitis B Surface Antigen,Antibodies to the Hepatitis C Virus,and Human Immunodeficiency Virus in a Hospital-Based Population in Jaipur,Rajasthan.Indian J Community Med.2010;35 (1):165-169.

5. Wu JF, Chang MH. Natural history of chronic hepatitis B virus infection from infancy to adult life-the mechanism of inflammation triggering and longterm impacts.J. BioMed Sci.2015;22:92: 1-7.

6 . Ananthanarayana R, Paniker CKJ, Text book of Microbiology, Universities Press(India) Private Limited 2003,9 th ed, pg:543-545.

7. Ocama P, Opio CK, Lee WM. HepatitisB virus infection: Current status. The American J Med. 2005;118,1413.e15-1413.e22.

8. Patel PA, Patel SP, Oza HV. Seroprevalence of Transfusion Transmitted Infections(TTIs) in Blood Donors at Western Ahmedabad-A secondary care Hospital Based Study.Int J Biol Med Res.2012;3(2): 1806-1810.

9. Supekar SN, Patel HL .Prevalence of Hepatitis B virus Infection in Young Students of Anand. Nat J Med Res 2012; 2(3):299-301.

10. Saraswathi KS, Aljabri F. The study of prevalence of Hepatitis B surface antigen during pregnancy in a tertiary care hospital,South India. Der Pharmacia Lettre, 2012,4(3):983-985.

11. Khaleel M, Syed A. Comparative study on Prevalence of Hepatitis B surface antigen among blood donors and in patient hospital attendees at a tertiary care hospital, Hyderabad. Ind J Bas Appl Med Resear 2016,5 (3):280-284.

12. Samatha P, Sireesha DM, Sowmya BS. Seroprevalence of Hepatitis B surface antigen , Antibodies to Hepatitis C&HIV in a hospital based population.J Biosci Tech 2015,6 (1):597-601.

13.Singh J, Bhatia R, Khare S, Patnaik SK ,Biswas S, Lal S et al. Community studies on prevalence of HBsAg in two urban populations of southern India.Ind Paeiatr 2000,37 (2):149-52.

14. Bhawani Y, Rao PR, Sudhakar V. Seroprevalence of transfusion transmissible infections among blood donors in a tertiary care hospital of Andhra Pradesh. Biology and Medicine 2010 ,2 (4):45-48.

15. Chandra M, Khaja MN, Farees N, Poduri CD, Hussain MM, Habeeb M , Habibullah CM. Prevalence, risk factors and genotype distribution of HCV and HBV infection in the tribal population :a community based study in South India. Tropical Gastro 2003,24 (4):193-195.

16. Batham A, Gupta MA, Rastogi P, et al .Calculating Prevalence of Hepatitis B in India: Using Population Weights to look for Publication Bias in Conventional Meta-analysis. Ind J Paed 2009 ;76:1247-1257.

Downloads

Published

23-02-2017

Issue

Section

Original Article

How to Cite

1.
Seroprevalence of Hepatitis B Surface Antigen positive Patients Attending a Tertiary Care Hospital in Srikakulam, Andhra Pradesh. Ann of Pathol and Lab Med [Internet]. 2017 Feb. 23 [cited 2025 Dec. 13];4(1):A96-99. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1118