Cytological and Histopathological Correlation of Breast Lump: A 3 Year Study at Tertiary Care Center
Keywords:
Cytology, Biopsy, Histopathology, Breast lumpAbstract
Background: The fine needle aspiration cytology (FNAC) is an OPD procedure that is easy to perform, accurate, reproducible and cheap. Fine needle aspiration is a part of triple test to diagnose the breast lump. However a definitive conclusion should always be reached through histopathological examination
Aim: The aim of our study is to correlate cytological diagnosis with histopathological diagnosis, to know clonicomorphologic spectrum of breast lump, and to figure out sensitivity, specificity, positive predictive value, negative predictive value and efficiency of FNAC.
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Methods: Total 244 cases who were subjected to FNAC and then subsequent biopsy was sent in each case were taken into consideration for analysis from tertiary care center in north Gujarat from February 2014 to January 2017 for 3 years.
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Results: In our study,4 were males and 240 were females(1.64% and 98.36% respectively). Maximum cases of breast lump were in the 21-30 years age group. Out of total 244 cases 154(63.11%) were benign, 50(20.49%) cases were malignant, 08 (3.27%) were suspicious for malignancy and 32(13.11%) were other nonneoplastic. Out of total 244 cases, 241 were consistent on histopathology and 3 were inconsistent. Our study have Sensitivity, Specificity, Positive predictive value, Negative predictive value, and Efficiency to be 98.24%, 98.93%, 96.55%, 99.46% and 98.77% respectively.
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Conclusion: FNAC helps the surgeon on further accurate management of lump as it is sensitive and specific. FNAC results should be correlated with clinical findings and radiological investigations. Inconclusive results and on FNAC should always be confirmed with biopsy.
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DOI:Â 10.21276/APALM.1380
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