Primary Splenic Lymphoma Presenting as Splenic Abscess: A Rare Entity
Keywords:
Primary, Lymphoma, Spleen, Abscess.Abstract
Primary splenic lymphoma are rare lymphomas which comprise less than 1% of the all malignant lymphoma. We present a case of 35 years old female with fever and pain in abdomen of a period of 20 days. The main purpose of this paper is to report a rare occurrence of primary splenic lymphoma and to demonstrate the possibility of it being misdiagnosed as splenic abscess clinically and on imaging.
References
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19. Mollejo M, Algara P, Mateo MS, Menárguez J, Pascual E, Fresno MF, et al. Large B-cell lymphoma presenting in the spleen: identification of different clinicopathologic conditions. Am J Surg Pathol. 2003;27(7):895-902.
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23. Sternberg, Stephen S., Stacey E Mills, and Darryl Carter. Sternberg's Diagnostic Surgical Pathology. 5th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2010.
24. Kim JK, Hahn JS, Kim GE, Yang WI. Three cases of diffuse large B-cell lymphoma presenting as primary splenic lymphoma. Yonsei Med J. 2005;46:703-9.
25. Healy NA, Conneely JB, Mahon S, O"²Riardon C, McAnena OJ. Primary splenic lymphoma presenting with ascites. Rare Tumors. 2011;3:e25
2. Giovagnoni A., Giorgi C., Goteri, G. Tumours of the spleen. Cancer Imaging. 2005;5(1): 73-77.
3. Li M, Zhang L, Wu N, Huang W, Lv N. Imaging findings of primary splenic lymphoma: A review of 17 cases in which diagnosis was made at splenectomy. PLoS One 2013;8:e80264
4. Falk S, Stutte H J. Primary malignant lymphomas of the spleen. A morphologic and immunohistochemical analysis of 17cases. Cancer. 1990;66:2612-2619
5. Ambulkar I, Kulkarni B, Borges A et al. Primary non-Hodgkin's lymphoma of the spleen presenting as space occupying lesion: a case report and review of literature. Leuk Lymphoma. 2006;47: 135-139
6. Konstantiadou I, Mastoraki A, Papanikolaou IS, Sakorafas G, Safioleas M. Surgical approach of primary splenic lymphoma: Report of a case and review of the literature. Indian J Hematol Blood Transfus. 2009;25:120-4.
7. Dasgupta T, Coombes B, Brasfield RD. Primary malignant neoplasms of the spleen. Surg Gynecol Obstet. 1965;120:947-60.
8. Skarin AT, Davey FR, Moloney WC. Lymphosarcoma of the spleen. Results of diagnostic splenectomy in 11 patients. Arch Intern Med. 1971; 127(2): 259—65.
9. Kehoe J, Straus DJ. Primary lymphoma of the spleen. Clinical features and outcome after splenectomy. Cancer. 1988; 62(7):1433—8.
10. Kraemer BB, Osborne BM, Butler JJ. Primary splenic presentation of malignant lymphoma and related disorders. A study of 49 cases. Cancer. 1984; 54(8):1606—19.
11. Cotta-Pereira R, Acar R, Mello CE, Iglesias AC, Basílio-de-Oliveira CA. Primary spleen lymphoma associated with hepatitis C virus infection. BMJ Case Rep. 2011;2011.
12. Kim JK, Hahn JS, Kim GE, Yang WI. Three cases of diffuse large B-cell lymphoma presenting as primary splenic lymphoma. Yonsei Med J. 2005;46:703-9.
13. Morel P, Dupriez B, Gosselin B, Fenaux P, Estienne MH, Facon T, et al. Role of early splenectomy in malignant lymphomas with prominent splenic involvement (Primary lymphomas of the spleen)- A study of 59 cases. Cancer. 1993;71(1):207—15.
14. Ahmann, D.L., Kiely, J.M., Harrison, E.G. Jr., Payne, W.S. Malignant lymphoma of the spleen: a review of 49 cases in which the diagnosis was made at splenectomy. Cancer. 1996;19(4):461-469.
15. Gobbi P, Grignani G, Pozzetti U, Bertoloni D, Pieresca C, Montagna G, et al. Primary splenic lymphoma: Does it exist? Haematologica. 1994;79:286—293.
16. Torlakovic E: Bone Marrow Workshop Prague 2012
17. Kraus MD, Fleming MD, Vonderheide RH. The spleen as a diagnostic specimen: a review of 10 years' experience at two tertiary care institutions. Cancer. 2001 Jun 1;91(11):2001-9.
18. Kashimura M, Naro M, Akikusa B, et al. Primary splenic DLBCL manifesting in red pulp. Virchows Arch. 2008;453:501—509.
19. Mollejo M, Algara P, Mateo MS, Menárguez J, Pascual E, Fresno MF, et al. Large B-cell lymphoma presenting in the spleen: identification of different clinicopathologic conditions. Am J Surg Pathol. 2003;27(7):895-902.
20. Craig FE, Foon KA. Flow cytometric immunophenotyping for hematologic neoplasms. Blood. 2008;111(8):3941-67.
21. Arcaini L, Lazzarino M, Colombo N, Burcheri S, Boveri E, Paulli M, et al. Splenic marginal zone lymphoma: a prognostic model for clinical use. Blood. 2006;107:4643-49.
22. Arcaini L, Paulli M. Splenic marginal zone lymphoma: hydra with many heads? Haematologica. 2010;95:534-537.
23. Sternberg, Stephen S., Stacey E Mills, and Darryl Carter. Sternberg's Diagnostic Surgical Pathology. 5th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2010.
24. Kim JK, Hahn JS, Kim GE, Yang WI. Three cases of diffuse large B-cell lymphoma presenting as primary splenic lymphoma. Yonsei Med J. 2005;46:703-9.
25. Healy NA, Conneely JB, Mahon S, O"²Riardon C, McAnena OJ. Primary splenic lymphoma presenting with ascites. Rare Tumors. 2011;3:e25
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03-10-2016
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Primary Splenic Lymphoma Presenting as Splenic Abscess: A Rare Entity. Ann of Pathol and Lab Med [Internet]. 2016 Oct. 3 [cited 2025 Dec. 13];3(4):C207-211. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm802
