Left Atrial Myxoma: An Enigma in Itself – Two Case Reports
DOI:
https://doi.org/10.21276/apalm.3724Keywords:
left atrial myxoma, case report, echocardiography, cardiac tumour, histopathologyAbstract
Background: Cardiac myxomas are rare primary cardiac tumours with variable clinical presentation.Case Presentation: We report two cases of left atrial myxoma, a 40-year-old female with dyspnoea and syncopal episodes, and a 16-year-old male with atypical chest pain and a prior neurological event. Routine laboratory parameters and ECG were unremarkable in both cases, while transthoracic echocardiography and CECT chest identified left atrial masses. Both patients underwent surgical excision. Histopathology revealed classic myxoma morphology with nests and cords of lepidic cells in a myxoid matrix. The older patient developed postoperative sepsis and expired, whereas the adolescent recovered uneventfully.Conclusion: These two case reports highlight the broad age spectrum and diverse clinical manifestations of left atrial myxoma, reinforcing the importance of timely imaging and histopathological confirmation.References
1. Bussani R, Castrichini M, Restivo L, Fabris E, Porcari A, Ferro F, Pivetta A, Korcova R, Cappelletto C, Manca P, Nuzzi V. Cardiac tumors: diagnosis, prognosis, and treatment. Current Cardiology Reports. 2020 Dec;22(12):169.
2. Li Y, Yang W, Liao S, Zuo H, Liu M. Cardiac myxomas as great imitators: a rare case series and review of the literature. Heart & Lung. 2022 Mar 1; 52:182-9.
3. Younes M, Al Mansour A, Al Halaki MJ, Lutfi L. A Case Report of Atrial Myxoma in the Time of Corona Presenting with Systemic Embolization. Dubai Medical Journal. 2022 Sep 29;5(3):212-6.
4. Khan Z, Yousif Y, Abumedian M, Ibekwe M, Warrier V, Muhammad SA, Gupta A. A case report on the incidental diagnosis of a left atrial myxoma in a patient presenting with right shoulder pain and inter-scapular back pain. Cureus. 2022 Mar 15;14(3).
5. Al-Zamkan BK, Hashem AM, Alaaeldin SA, Abdel Aziz M. An exceptionally giant left atrial myxoma: a case report and literature review. European Heart Journal-Case Reports. 2020 Dec;4(6):1-7.
6. Thakur D, Sridhar A, Solomon NA. An Unusual Presentation of Left Atrial Myxoma in an Adolescent. International Journal of Clinical Pediatrics. 2018 Jan 4; 6(3-4):46-50.
7. Islam AM. Cardiac myxomas: a narrative review. World Journal of Cardiology. 2022 Apr 26;14(4):206.Akiki E, Arghami A, Abbasi MA, El-Am EA, Ahmad A, Foley TA, Daly RC, Maleszewski JJ, Kurmann R, Klarich KW. Case Report: A myxoma with a far reach. Frontiers in Cardiovascular Medicine. 2024 Jan 24; 11:1340406.
8. Nathaniel M, Mercer MK, Dhiraj B. Diagnosis and Treatment of Cardiac Myxoma. Cureus. 2023;15(5).
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Copyright (c) 2026 Fiza Chopra, Neha Singh, Rupinder Kaur, Sanjukta

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