Leiomyosarcoma with unknown primary

Authors

  • Manika Khare JNU HOSPITAL, INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE
  • Ashish Airun JNU HOSPITAL, INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE
  • Umesh Babu Sharma JNU HOSPITAL, INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE
  • S K Jain JNU HOSPITAL, INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE

Keywords:

Leiomyosarcoma, Multiocal, Poor Prognosis

Abstract

Leiomyosarcoma is a malignant tumor which do not arise from the leiomyoma. Leiomyosarcoma is an extremely rare form of cancer and accounts for 5–10% of soft tissue sarcomas,  which are in themselves relatively rare. This case report shows unusual presentation of the multofocal leiomyosarcoma along with diagnostic dilemma. The prognosis and treatment modality are also discussed in the discussion.

 

 

DOI: 10.21276/APALM.1231

References

1. Horvai A. Bones, Joints and Soft Tissue Tumors. In: Kumar V, Abbas, AK, Aster JC, editors. Pathological Basis of Disease. 9 Edition. Philadelphia: Elsevier; 2015: 1179-226.
2. Weaver MJ, Abraham JA. Leiomyosarcoma of the Bone and Soft Tissue: A Review. ESUN.2007;4:2.
3. Basic info". www.leiomyosarcoma.info. LMS leiomyosarcoma
4. Golden T, Stout AP. Smooth muscle tumors of the gastrointestinal tract and retroperitoneal tissues. Surg Gynecol Obstet.1941;73:784.
5. Evans HL., Shipley J. Leimyosarcoma. In: Christopher D.M. Fletcher, K. Krishnan Unni, Fredrik Mertens, editors. World Health Organization Classification of Tumours, Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: 2002. 131-34.

6. Fridie IL, Hong IS, Green WR. Multicentric gastrointestinal and extraintestinal leiomyosarcomatosis: a case report. J Natl Med Assoc.1992;84:7.
7. Roth JA, Carter H, Costabile DAn unusual multifocal leiomyosarcoma of the stomach: a light and electron microscopic study. Hum Pathol.1978;9:3.
8. Rodriguez FJ, Folpe AL, Giannini C, Perry A Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathol. 2012;123:3.
9. Schurch W, Skalli O, Seemayer TA, Gabbiani G. Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. I. Smooth muscle tumors. Am J Pathol. 1987;128.
10. Juang CM, Yen MS, Horng HC, Twu NF, Yu HC, Hsu WL. Potential role of preoperative serum CA125 for the differential diagnosis between uterine leiomyoma and uterine leiomyosarcoma. Eur J Gynaecol Oncol. 2006;27:4:370.
11. Vellanki VS, Rao M, Sunkavalli CB, Chinamotu RN, Kaja S. A rare case of uterine leiomyosarcoma: a case report. J Med Case Rep. 2010;4:222.
12. Kandel R, Coakley N, Werier J, Engel J, Ghert M, Verma S. Surgical margins and handling of soft-tissue sarcoma in extremities: a clinical practice guideline. Curr Oncol. 2013;20:3.
13. Mankin, HJ, Casas-Ganem, J, Kim, JI, et al. Leiomyosarcoma of somatic soft tissues. Clin Orthop Relat Res. 2004;421.

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Published

25-08-2017

How to Cite

1.
Khare M, Airun A, Sharma UB, Jain SK. Leiomyosarcoma with unknown primary. Ann of Pathol and Lab Med [Internet]. 2017 Aug. 25 [cited 2024 Nov. 2];4(4):C106-109. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm1231

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Section

Case Report