Secretory carcinoma breast: A rare cytodiagnosis.

Authors

  • Ankit Kaushik VMMC and Safdarjung Hospital, GGSIPU
  • Mukul Singh VMMC and Safdarjung Hospital, Delhi
  • Sachin Kolte VMMC and Safdarjung Hospital, Delhi
  • Kusum Gupta
  • A K Mandal

Keywords:

Secretory Carcinoma, Breast, FNAC

Abstract

Secretory carcinoma is a rare low grade malignant breast carcinoma of children and adults. Since patients are often young and presents with indolent breast lump in the breast, a high degree of suspicion is often needed for the clinical diagnosis. Fine needle aspiration cytology (FNAC) is often the primary investigation, and because of the indolent clinical presentation, rarity of tumour and unanticipated cytological findings a primary cytological diagnosis of secretory carcinoma is often difficult.

We present a case of 13-year-old female, presented with a well defined mobile  right breast lump. The aspiration cytology revealed highly cellular smears consisted of singly scattered and loosely cohesive cluster of monomorphic cell population of round to ovoid cells with bland cytological appearance in background of thick mucinous material, leading to cytological diagnosis of secretory carcinoma.

 A primary diagnosis of secretory carcinoma on FNAC can provide early and definite surgical management including simple mastectomy with axillary lymph node resection recommended for treatment of secretory carcinoma.

References

1. Botta G, Fessia L, Ghiringhello B. Juvenile milk protein secreting carcinoma. Virchows Arch A Pathol Anat Histol.1982; 395: 145-52.

2. Lamovec J, Bracko M . Secretory carcinoma of the breast: light microscopical, immunohistochemical and flow cytometric study. Mod Pathol. 1994;7: 475-9.

3. Rosen PP, Cranor ML. Secretory carcinoma of the breast. Arch Pathol Lab Med. 1991; 115: 141-4.

4. Shanthi V, Rama Krishna BA, Rao NM, Sujatha C. Cytodiagnosis of secretory carcinoma of the breast. J Cytol. 2012 Jan-Mar; 29(1): 63-5.

5. Jayaram G, Looi LM, Yip CH. Fine needle aspiration cytology of secretory carcinoma of breast: a case report. Malays J Pathol. 1997;19:69-73.

6. Lamovec J, Bracko M . Secretory carcinoma of the breast: light microscopical, immunohistochemical and flow cytometric study. Mod Pathol.1994; 7: 475- 9.

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Published

25-02-2016

How to Cite

1.
Kaushik A, Singh M, Kolte S, Gupta K, Mandal AK. Secretory carcinoma breast: A rare cytodiagnosis. Ann of Pathol and Lab Med [Internet]. 2016 Feb. 25 [cited 2024 Dec. 26];3(1):C53-55. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm249

Issue

Vol. 3 No. 1 (2016)

Section

Case Report

License

Copyright (c) 2016 Ankit Kaushik, Mukul Singh, Sachin Kolte, Kusum Gupta, A K Mandal

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