Non-leukemic granulocytic sarcoma presenting as multiple skin nodules: A rare case report
Keywords:
Bone marrow, fine needle aspiration cytology, flow-cytometry examination, non-leukemic granulocytic sarcomaAbstract
Granulocytic sarcoma (GS) is a localized lesion comprising of immature granulocytes, monocytes, or both; involving extramedullary sites. GS with no evidence of leukemia (non-leukemic GS) is a very rare. Here we report a 10 year old male child who presented with facial and back swelling which was subsequently diagnosed as non-leukemic GS by flow-cytometry (FCM) examination on aspirated material.
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2. Yamauchi K, Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma: Report of two cases and a review of 72 cases in the literature. Cancer 2002; 94:1739–46.
3. King A. A case of chloroma. Monthly J Med 1853; 17: 97.
4. RodrÃguez Guerrero JM, MartÃn Hidalgo JR, Alonso Alejandro E, Pérez RÃos N, Roussel J, RodrÃguez Pardo F et al. Granulocytic sarcoma (chloroma) of small bowel: an infrequent cause of intestinal obstruction. Gastroenterol Hepatol 2003; 26: 347–50.
5. Bénet C, Gomez A, Aguilar C, Delattre C, Vergier B, Beylot- Barry M, et al. Histologic and immunohistologic characterization of skin localization of myeloid disorders: a study of 173 cases. Am J Clin Pathol 2011;135: 278–290.
6. Audouin J, Comperat E, Le Tourneau A, Camilleri-Broët S, Adida C, Molina T et al. Myeloid sarcoma: clinical and morphologic criteria useful for diagnosis. Int J Surg Pathol. 2003; 11: 271-82.
7. Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE et al. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases. Cancer 1981; 48: 1426-37.
8. Spahr J, Behm FG, Schneider V. Preleukemic granulocytic sarcoma of cervix and vagina: initial manifestation by cytology. Acta Cytol 1982; 26: 55-60.
9. Krause JR. Granulocytic sarcoma preceding acute leukemia: a report of six cases. Cancer 1979; 44: 1017-21.
10. Lan TY, Lin DT, Tien HF, Yang RS, Chen CY, Wu K. Prognostic factors of treatment outcomes in patients with granulocytic sarcoma. Acta Haematol. 2009; 122: 238-46.
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Published
25-02-2016
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1.
Agrawal P, Kumar N, Bansal D, Nijhawan R. Non-leukemic granulocytic sarcoma presenting as multiple skin nodules: A rare case report. Ann of Pathol and Lab Med [Internet]. 2016 Feb. 25 [cited 2024 Dec. 26];3(1):C19-22. Available from: https://pacificejournals.com/journal/index.php/apalm/article/view/apalm473
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Copyright (c) 2016 Pallavi Agrawal, Narender Kumar, Deepak Bansal, Raje Nijhawan
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